Rab27a Regulates Exocytosis of Tertiary and Specific Granules in Human Neutrophils
نویسندگان
چکیده
منابع مشابه
Rab27a regulates exocytosis of tertiary and specific granules in human neutrophils.
The correct mobilization of cytoplasmic granules is essential for the proper functioning of human neutrophils in host defense and inflammation. In this study, we have found that human peripheral blood neutrophils expressed high levels of Rab27a, whereas Rab27b expression was much lower. This indicates that Rab27a is the predominant Rab27 isoform present in human neutrophils. Rab27a was up-regul...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2008
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.181.6.3793